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Faculté Sciences de base - FSB
Ecole Polytechnique Fédérale de Lausanne
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Welcome to Laboratory of Physics of Living Matter
Bienvenue au laboratoire de physique de la matière vivante -
LPMV
The Laboratory of Physics of Living Matter (LPMV) is part of Institute of Physics of Biological Systems the Faculty of Basic Sciences (FSB) of the Swiss Federal Institute of Technology (EPFL).

The Laboratory is situated at the forth floor in the BSP/Cubotron (Bâtiment des sciences physiques UNIL) , west of the Dorigny campus of Lac Leman Border (site map)
Research Activities
Prof. Giovanni DietlerThe research activity of the laboratory of physics of living matter is mainly devoted to the study of DNA topology, cellular machines, protein mechanics and high-resolution low temperature Atomic Force Microscopy (AFM). Through internal and external collaborations, a certain number of other research activities are carried out in particular on knots hydrodynamics, DNA gel electrophoresis, cell elasticity, cell motility, etc.

The DNA topology activity is mainly centered on the statistical physics of linear and knotted DNA and the scaling exponents for linear DNA were recently determined by AFM.
Concerning the protein mechanics we have developed a new method to determine the spring constant of a single protein by AFM. Cellular machines, like chaperonin, are studied at the single molecule level with the aim of understanding their detailed function.

High resolution AFM at low temperature (liquid nitrogen temperature) is under development in our laboratory. This technique relies on the fact that polymers (such as proteins or DNA) becomes stiff as the temperature is lowered, thus we expect anincrease in resolution for the AFM.


Seminars - Doctoral School - Workshops
Seminars of Biological Physics
Monday, March 29 – Cubotron/BSP 407 – 11h15

Novel Multiphoton Microscopy Techniques for Cell Imaging:CARS Microscopy and Resonant Four-Wave Mixing
Paola Borri
School of Biosciences, Cardiff University
Events

FSB people: Promotions et nominations de Professeurs

Les professeurs Paolo De Los Rios (ITP-LBS)  et Vincenzo Savona (ITP-GR-SA) viennent d'être promus Professeur Associé lors de la dernière réunion du Conseil des EPF.

ERC had also awarded Prof. Suliana Manley with an "European Research Council 2009 Starting Grant" for Life Sciences.
Project Title: Protein assembly: From the molecular scale to the mesoscale with super-resolution imaging

Publications

Persistence length and scaling properties of single-stranded DNA adsorbed on modified graphite
Rechendorff, K ; Witz, G; Adamcik, J ; Dietler, G
JOURNAL OF CHEMICAL PHYSICS, 131 (9): Art. No. 095103 SEP 7 2009

Stiffness Tomography by Atomic Force Microscopy
Roduit, C ; Sekatski, S ; Dietler, G ; Catsicas, S ; Lafont, F ; Kasas, S
BIOPHYSICAL JOURNAL, 97 (2): 674-677 JUL 22 2009

Complex studies of interactions between flaviviruses and laminin binding protein
Bogachek, M ; Protopopova, E ; Loktev, V ; Zaitsev, B ; Favre, M ; Sekatskii, S ; Dietler, G
34th Congress of the Federation-of-European-Biochemical-Societies, Prague CZECH REPUBLIC

Intracellular nanomanipulation by a photonic-force microscope with real-time acquisition of a 3D stiffness matrix
Bertseva, E ; Singh, ASG ; Lekki, J ; Thevenaz, P ; Lekka, M ; Jeney, S ; Gremaud, G ; Puttini, S ; Nowak, W ; Dietler, G ; Forro, L ; Unser, M ; Kulik, AJ
NANOTECHNOLOGY, 20 (28): Art. No. 285709 JUL 15 2009
Registration of long-range surface plasmon resonance by angle-scanning feedback and its implementation for optical hydrogen sensing
Konopsky, VN ; Basmanov, DV ; Alieva, EV ; Dolgy, DI ; Olshansky, ED ; Sekatskii, S ; Dietler, G
NEW JOURNAL OF PHYSICS   Volume: 11 Article Number: 063049   Published: JUN 30 2009
Temperature-Controled assembly of highly ordered/disordered dodecylamine layers on HOPG: Consequences for DNA patterning
Jozef Adamcik, Susana Tobenas, Giovanni di Santo, Dmitri Klinov, Giovanni Dietler
LANGMUIR  25  issue 5, 3159-3162  (2009)
Head
Prof. Giovanni Dietler
giovanni.dietler[@]epfl.ch

Prof. Giovanni Dietler
Office BSP/Cubotron 409
Phone +41 (0)21 6930446
Fax +41 (0)21 6930422
Secretary
Christine Vuichoud
Office BSP/Cubotron 410
Phone +41 (0)21 6930443
Fax +41 (0)21 6930422

Postal Adress
EPFL SB IPSB
BSP/CUBOTRON (Bât. sciences physiques UNIL)
CH-1015 Lausanne

Members
Office
Phone
Serguei Sekatski
Fabrizio Benedetti
Kanat Dukenbayev
BSP 408
30445

Sandor Kasas
Charles Roduit
Liva Alonso

BSP 411
30458

Jae Sun Jeong
Mounir Mensi
Suriya Murthy Nagamani

BSP 413
30461 
Kristian Rechendorff
Guillaume Witz
BSP 414
34521   

Andrzej Kulik
Caroline Maillard
Carine Ben Adiba

BSP 417
33359
30464
Dusan Vobornik
Andrea Cerreta
BSP 422
30455
Malgorzata Lekka
Piotr Marszalek

BSP 423

Laurent Braun BSP 523
34520
Michel Kessous
BSP 429
30454
Jean-Luc Baumberger
BSP 126
304020

Laboratories
Chemical Lab
BSP 228
30424
AFM/Nanoscope
BSP 226
30429
SNOM
BSP 225
30423
CryoAFM
BSP 224
30428
BiosCope
and SNOM
BSP 221
30450
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© 2009, EPFL - EPFL SB IPSB - BSP/Cubotron (Bât. sciences physiques UNIL) CH-1015 Lausanne , Switzerland - Tel: +41 021 6930443, Fax: +41 021 6930422
 
 

michel.kessous[@]epfl.ch - Last Update: March 18, 2010