Welcome to Laboratory of Physics of Living Matter
Bienvenue au laboratoire de physique de la matière vivante - LPMV
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The Laboratory of Physics of Living Matter (LPMV) is part of Institute of Physics of Biological Systems the Faculty of Basic Sciences (FSB) of the Swiss Federal Institute of Technology (EPFL).
The Laboratory is situated at the forth floor in the BSP/Cubotron (Bâtiment des sciences physiques UNIL) , west of the Dorigny campus of Lac Leman Border (site map) |
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| Research Activities |
 The research activity of the laboratory of physics of living matter is mainly devoted to the study of DNA topology, cellular machines, protein mechanics and high-resolution low temperature Atomic Force Microscopy (AFM). Through internal and external collaborations, a certain number of other research activities are carried out in particular on knots hydrodynamics, DNA gel electrophoresis, cell elasticity, cell motility, etc.
The DNA topology activity is mainly centered on the statistical physics of linear and knotted DNA and the scaling exponents for linear DNA were recently determined by AFM.
Concerning the protein mechanics we have developed a new method to determine the spring constant of a single protein by AFM. Cellular machines, like chaperonin, are studied at the single molecule level with the aim of understanding their detailed function. |
High resolution AFM at low temperature (liquid nitrogen temperature) is under development in our laboratory. This technique relies on the fact that polymers (such as proteins or DNA) becomes stiff as the temperature is lowered, thus we expect anincrease in resolution for the AFM.
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Seminars - Doctoral School - Workshops
Seminars of Biological Physics
Monday, March 29 – Cubotron/BSP 407 – 11h15
Novel Multiphoton Microscopy Techniques for Cell Imaging:CARS Microscopy and Resonant Four-Wave Mixing
Paola Borri
School of Biosciences, Cardiff University |
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| Events |
FSB people: Promotions et nominations de Professeurs
Les professeurs Paolo De Los Rios (ITP-LBS) et Vincenzo Savona (ITP-GR-SA) viennent d'être promus Professeur Associé lors de la dernière réunion du Conseil des EPF.
ERC had also awarded Prof. Suliana Manley with an "European Research Council 2009 Starting Grant" for Life Sciences.
Project Title: Protein assembly: From the molecular scale to the mesoscale with super-resolution imaging |
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Publications
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Persistence length and scaling properties of single-stranded DNA adsorbed on modified graphite
Rechendorff, K ; Witz, G; Adamcik, J ; Dietler, G
JOURNAL OF CHEMICAL PHYSICS, 131 (9): Art. No. 095103 SEP 7 2009
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Stiffness Tomography by Atomic Force Microscopy
Roduit, C ; Sekatski, S ; Dietler, G ; Catsicas, S ; Lafont, F ; Kasas, S
BIOPHYSICAL JOURNAL, 97 (2): 674-677 JUL 22 2009
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Complex studies of interactions between flaviviruses and laminin binding protein
Bogachek, M ; Protopopova, E ; Loktev, V ; Zaitsev, B ; Favre, M ; Sekatskii, S ; Dietler, G
34th Congress of the Federation-of-European-Biochemical-Societies, Prague CZECH REPUBLIC
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Intracellular nanomanipulation by a photonic-force microscope with real-time acquisition of a 3D stiffness matrix
Bertseva, E ; Singh, ASG ; Lekki, J ; Thevenaz, P ; Lekka, M ; Jeney, S ; Gremaud, G ; Puttini, S ; Nowak, W ; Dietler, G ; Forro, L ; Unser, M ; Kulik, AJ
NANOTECHNOLOGY, 20 (28): Art. No. 285709 JUL 15 2009
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Registration of long-range surface plasmon resonance by angle-scanning feedback and its implementation for optical hydrogen sensing
Konopsky, VN ; Basmanov, DV ; Alieva, EV ; Dolgy, DI ; Olshansky, ED ; Sekatskii, S ; Dietler, G
NEW JOURNAL OF PHYSICS Volume: 11 Article Number: 063049 Published: JUN 30 2009
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Temperature-Controled assembly of highly ordered/disordered dodecylamine layers on HOPG: Consequences for DNA patterning
Jozef Adamcik, Susana Tobenas, Giovanni di Santo, Dmitri Klinov, Giovanni Dietler
LANGMUIR 25 issue 5, 3159-3162 (2009)
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Head
Prof.
Giovanni Dietler
giovanni.dietler[@]epfl.ch
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| Office |
BSP/Cubotron 409 |
| Phone |
+41 (0)21 6930446 |
| Fax |
+41 (0)21 6930422 |
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Secretary |
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| Office |
BSP/Cubotron 410 |
| Phone |
+41 (0)21 6930443 |
| Fax |
+41 (0)21 6930422 |
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Postal
Adress
EPFL SB IPSB
BSP/CUBOTRON (Bât. sciences physiques UNIL)
CH-1015 Lausanne |
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Members |
Office
Phone |
Serguei Sekatski
Fabrizio Benedetti
Kanat Dukenbayev |
BSP 408
30445 |
Sandor Kasas
Charles Roduit
Liva Alonso
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BSP 411
30458 |
Jae Sun Jeong
Mounir Mensi
Suriya Murthy Nagamani |
BSP 413
30461 |
Kristian Rechendorff
Guillaume Witz |
BSP 414
34521 |
Andrzej Kulik
Caroline Maillard
Carine Ben Adiba |
BSP 417
33359
30464
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Dusan Vobornik
Andrea Cerreta |
BSP 422
30455 |
Malgorzata Lekka
Piotr Marszalek
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BSP 423
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| Laurent Braun |
BSP 523
34520 |
Michel Kessous |
BSP 429
30454 |
Jean-Luc Baumberger |
BSP 126
304020
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Laboratories
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| Chemical Lab |
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| AFM/Nanoscope |
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| SNOM |
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| CryoAFM |
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BiosCope
and SNOM |
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| Useful Links
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